Audiovisualization of neural activity and blood flow from the dorsal surface of the thinned skull cortex of the awake mouse. Behavioral data (top), neuronal activity (GCaMP6f) (bottom left), and cortical hemodynamics (bottom right). Webcam data was acquired simultaneously using two PS3 Eye webcams. Raw GCaMP data was k-means clustered to derive regions of interest (ROIs) from which to extract 12 basis time-courses from both neural and hemodynamic data-streams. Corresponding spatial components fitting a linear model to the original data were derived using non-negative least-squares fitting. Spatial components were then color-coded and re-combined for both datasets, with colors from the Matlab™ jet color map ordered from the front (top, red) to the back (bottom, blue) of the brain. Time-courses for each ROI were converted into audible representations, combined in the movie’s soundtrack as piano notes for neural activity and violin as hemodynamics. Note: Movie has sound.