Meldrew began making Flash cartoons in his bedroom as a teenager during the early days of Web 1.0, immersed in London's early grime scene. Missy Elliott and Channel U picked up his cartoons, which gave him an early boost. Over the following two decades, he continued collaborating with a range of grime and dubstep musicians on visual work. He set up an early grime website and forum while based in London during Web 1.0's early years. By the mid-to-late 2000s he had moved to Bristol for university, where he lent his design, animation and VJ skills to the growing dubstep scene. There he worked with record labels, event organisers and artists tied to that scene.²

His entry into digital art came through designing rave flyers in the early 1990s and 2000s, some digital and others airbrushed with a digital feel, often futuristic, abstract, surreal or psychedelic. Artists such as Pez, Art Jaz and Junior Tomlin were early influences, admired for creating entirely fictional worlds with cultural symbolism. That fascination with intricate, immersive world-building carried into his later animation and NFT work, where he uses surreal imagery to explore decentralisation and the strength of online communities.² In 2022 he created Broadside Episode #1 - n00b, part of Broadside, an NFT storyworld whose CC0-licensed character collectibles let holders create their own work within it.³