The most important scientific revolutions all include, as their only common feature, the dethronement of human arrogance from one pedestal after another of previous convictions about our centrality in the cosmos.'' Our very own enhanced scientific abilities are undermining our delusion of human centrality to the universe. While 2021 triggering a motion of re-vision and re-definition of the concept of being human, the world is witnessing a species-wise blurring of boundaries that shifting the paradigm in the perception of the human body. We are witnessing the first sprouts of organic and machine intertwine, which is not so different than the initial steps of microorganisms having to switch and grow to more complex entities hundreds of million years ago. We already started to see the primitive examples of our future ancestors combining technology, biology, and awareness. The symbiosis between machine and organic is a new chapter into our future, but what should be our focus as we design and implement human-machine symbiosis for the purpose of reaching the next step for mankind?